Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696581 | 0.83 | ALDH1A1 (0.44) | ALDH1A1TDP1L3MBTL1MAPK1NTRK1 | |
| SCHEMBL454098 | 0.78 | ALDH1A1 (0.48) | ALDH1A1TDP1L3MBTL1MAPK1NTRK1 | |
| SCHEMBL473919 | 0.76 | ALDH1A1 (0.51) | ALDH1A1TDP1L3MBTL1MAPK1MAPT | |
| SCHEMBL29726958 | 0.76 | ALDH1A1 (0.51) | ALDH1A1TDP1L3MBTL1MAPK1MAPT | |
| Butane SCHEMBL9696577 | 0.73 | ALDH1A1 (0.45) | ALDH1A1TDP1L3MBTL1MAPK1NTRK1 | |
| SCHEMBL24198765 | 0.73 | KMT2A (0.46) | ALDH1A1TDP1L3MBTL1MAPK1MAPT | |
| SCHEMBL15202917 | 0.73 | TDP1 (0.50) | ALDH1A1TDP1L3MBTL1MAPK1MAPT | |
| SCHEMBL8342298 | 0.72 | ELANE (0.48) | ALDH1A1TDP1L3MBTL1MAPK1NTRK1 | |
| SCHEMBL8337219 | 0.72 | ALDH1A1 (0.48) | ALDH1A1TDP1L3MBTL1MAPK1KMT2A | |
| SCHEMBL31050105 | 0.72 | ALDH1A1 (0.61) | ALDH1A1TDP1L3MBTL1MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149822-A | PREPARATION OF 2,3-DICHLORO-5-ACETYLPYRIDINE | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-22 | — | — | US | disclosed |