Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7390395 | 0.91 | KLK7 (0.40) | KLK7CYP3A4ALDH1A1MAPTABCB1 | |
| SCHEMBL16312232 | 0.90 | KLK7 (0.39) | KLK7CYP3A4ALDH1A1MAPTABCB1 | |
| SCHEMBL17776302 | 0.88 | KLK7 (0.40) | KLK7CYP3A4ALDH1A1MAPTABCB1 | |
| SCHEMBL9697292 | 0.87 | CYP3A4 (0.38) | KLK7CYP3A4ALDH1A1MAPTABCB1 | |
| SCHEMBL17764781 | 0.87 | CYP3A4 (0.38) | KLK7CYP3A4ALDH1A1MAPTABCB1 | |
| SCHEMBL17764780 | 0.87 | CYP3A4 (0.38) | KLK7CYP3A4ALDH1A1MAPTABCB1 | |
| SCHEMBL17764779 | 0.87 | CYP3A4 (0.38) | KLK7CYP3A4ALDH1A1MAPTABCB1 | |
| SCHEMBL17776301 | 0.86 | CTSS (0.39) | KLK7CYP3A4ALDH1A1MAPTABCB1 | |
| SCHEMBL17776306 | 0.85 | KLK7 (0.36) | KLK7CYP3A4ALDH1A1MAPTKLK5 | |
| SCHEMBL16312215 | 0.84 | TAAR1 (0.39) | ALDH1A1MAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481311-A2 | Aminoacid derivatives | MERCK PATENT GmbH (DE) | 1992-04-22 | — | — | EP | disclosed |