Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | USP8 | P40818 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377077 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CYP3A4TSHRHSD17B10MAPK1 | |
| SCHEMBL28787888 | 0.72 | TSHR (0.46) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL9696332 | 0.72 | CHRNA7 (0.49) | ALDH1A1TSHRHSD17B10MAPK1HPGD | |
| SCHEMBL2855783 | 0.72 | CHRNA7 (0.49) | ALDH1A1TSHRHSD17B10MAPK1HPGD | |
| SCHEMBL28698643 | 0.71 | TSHR (0.44) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL14690479 | 0.71 | ALDH1A1 (0.39) | ALDH1A1TSHRHSD17B10MAPK1HPGD | |
| SCHEMBL7718084 | 0.70 | ALDH1A1 (0.48) | ALDH1A1TSHRHSD17B10MAPK1MEN1 | |
| SCHEMBL7718086 | 0.70 | ALDH1A1 (0.48) | ALDH1A1TSHRHSD17B10MAPK1MEN1 | |
| SCHEMBL2855782 | 0.69 | MEN1 (0.64) | ALDH1A1MAPK1MEN1KMT2APKM | |
| SCHEMBL6381569 | 0.69 | MEN1 (0.44) | ALDH1A1TSHRHSD17B10MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992000547-A1 | POLYMERIC COMPOSITIONS | BRITISH TELECOMMUNICATIONS PUBLIC LIMITED COMPANY (GB) | 1992-01-09 | — | — | WO | disclosed |