Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 5/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2005428 | 1.00 | PPM1B (0.44) | PPM1BPTPN1PPP1CCKMT2AMEN1 | |
| SCHEMBL2002666 | 1.00 | PPM1B (0.44) | PPM1BPTPN1PPP1CCKMT2AMEN1 | |
| SCHEMBL26844637 | 0.92 | PPM1B (0.40) | PPM1BPTPN1PPP1CCKMT2AMEN1 | |
| SCHEMBL1008906 | 0.92 | PPM1B (0.56) | PPM1BPTPN1PPP1CCKMT2AMEN1 | |
| SCHEMBL10083154 | 0.92 | PPM1B (0.56) | PPM1BPTPN1PPP1CCKMT2AMEN1 | |
| SCHEMBL16788624 | 0.92 | PPM1B (0.56) | PPM1BPTPN1PPP1CCKMT2AMEN1 | |
| SCHEMBL19388139 | 0.92 | PPM1B (0.56) | PPM1BPTPN1PPP1CCKMT2AMEN1 | |
| SCHEMBL16790508 | 0.92 | PPM1B (0.56) | PPM1BPTPN1PPP1CCKMT2AMEN1 | |
| SCHEMBL7715585 | 0.87 | PPM1B (0.37) | PPM1BPTPN1PPP1CCKMT2AMEN1 | |
| SCHEMBL13888451 | 0.86 | PPM1B (0.39) | PPM1BPTPN1PPP1CCKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084539-A | Ring opening polymerization of cyclic olefins useful in water treatment | CIBA-GEIGY CORPORATION (US) | 1992-01-28 | — | — | US | disclosed |