SCHEMBL1008906

SCHEMBL1008906

COC(=O)C1C2C=CC(O2)C1C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 5/20 0.56
KMT2A Q03164 3/20 0.53
MEN1 O00255 1/20 0.53
PTPN1 P18031 1/20 0.52
PPP1CC P36873 1/20 0.52
ALDH1A1 P00352 5/20 0.51
KDM4E B2RXH2 2/20 0.50
POLB P06746 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.45
TP53 P04637 1/20 0.45
GAA P10253 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
USP2 O75604 1/20 0.43
TSHR P16473 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10083154 1.00 PPM1B (0.56) PPM1BKMT2AMEN1PTPN1PPP1CC
SCHEMBL16788624 1.00 PPM1B (0.56) PPM1BKMT2AMEN1PTPN1PPP1CC
SCHEMBL16790508 1.00 PPM1B (0.56) PPM1BKMT2AMEN1PTPN1PPP1CC
SCHEMBL19388139 1.00 PPM1B (0.56) PPM1BKMT2AMEN1PTPN1PPP1CC
SCHEMBL2002666 0.92 PPM1B (0.44) PPM1BKMT2AMEN1PTPN1PPP1CC
SCHEMBL9696402 0.92 PPM1B (0.44) PPM1BKMT2AMEN1PTPN1PPP1CC
SCHEMBL2005428 0.92 PPM1B (0.44) PPM1BKMT2AMEN1PTPN1PPP1CC
SCHEMBL26844637 0.84 PPM1B (0.40) PPM1BKMT2AMEN1PTPN1PPP1CC
SCHEMBL3818435 0.83 PPM1B (0.50) PPM1BKMT2AMEN1ALDH1A1KDM4E
SCHEMBL238046 0.83 PPM1B (0.50) PPM1BKMT2AMEN1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230341777-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING TERMINAL-BLOCKED REACTION PRODUCT NISSAN CHEMICAL CORPORATION (JP) 2023-10-26 US disclosed
US-20230296984-A1 EUV RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-09-21 US disclosed
US-20230259028-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING REACTION PRODUCT OF HYDANTOIN COMPOUNDS NISSAN CHEMICAL CORPORATION (JP) 2023-08-17 US disclosed
US-20230259028-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING REACTION PRODUCT OF HYDANTOIN COMPOUNDS NISSAN CHEMICAL CORPORATION (JP) 2023-08-17 US disclosed
US-20180127520-A1 METHOD FOR PRODUCING RING-OPENING METATHESIS POLYMER HYDRIDE, AND RESIN COMPOSITION ZEON CORPORATION (JP) 2018-05-10 US disclosed
US-9850325-B2 Method for producing ring-opening metathesis polymer hydride, and resin composition ZEON CORPORATION (JP) 2017-12-26 US disclosed
US-9770511-B2 Protein transduction domains mimics UNIVERSITY OF MASSACHUSETTS (US) 2017-09-26 US disclosed
US-20160324970-A1 PROTEIN TRANSDUCTION DOMAINS MIMICS UNIV MASSACHUSETTS (US) 2016-11-10 US disclosed
EP-2270063-B1 PROCESS FOR PRODUCING HYDROGENATED PRODUCT OF CYCLIC OLEFIN POLYMER PREPARED THROUGH RING-OPENING POLYMERIZATION ZEON CORP (JP) 2016-03-23 EP disclosed
US-20150051353-A1 METHOD FOR PRODUCING RING-OPENING METATHESIS POLYMER HYDRIDE, AND RESIN COMPOSITION ZEON CORPORATION (JP) 2015-02-19 US disclosed
US-20050014916-A1 Ruthenium complexes, process for preparation thereof, and processes for producing open-ring polymer of cycloolefins and hydrogenation products thereof by using the complex as catalyst ZEON CORPORATION (JP) 2005-01-20 US disclosed
EP-1048350-B1 Polymeric homogeneous catalysts DEGUSSA (DE) 2004-06-02 EP disclosed
EP-0776924-B1 Polyimide composition and method for producing prepreg and paint using the same MITSUBISHI HEAVY IND LTD (JP) 2003-09-24 EP disclosed
US-20030050406-A1 Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization ZEON CORPORATION 2003-03-13 US disclosed
US-6486264-B1 Process for producing hydrogenated ring-opening polymerization polymer of cycloolefin ZEON CORPORATION (JP) 2002-11-26 US disclosed
US-6403522-B1 CONTAINING AN UNSATURATED POLYMER BACKBONE GENERATED BY RING OPENING METATHESIS POLYMERIZATION; MORE RIGID; REACTING A RUTHENIUM OR MOLYBDENUM CARBENE CATALYST WITH A BICYCLIC OLEFIN DEGUSSA AG (DE) 2002-06-11 US disclosed
EP-1197509-A1 PROCESS FOR PRODUCING HYDROGENATED RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN Nippon Zeon Co., Ltd. (JP) 2002-04-17 EP disclosed
EP-1048350-A1 Polymeric homogeneous catalysts Degussa-Hüls Aktiengesellschaft (DE) 2000-11-02 EP disclosed
US-5914385-A Polyimide resin composition and method for producing prepreg and paint and method for curing resin using the same MITSUBISHI JUKOGYO KABUSHIKI KAISHA (JP) 1999-06-22 US disclosed
EP-0776924-A2 Polyimide composition and method for producing prepreg and paint using the same MITSUBISHI JUKOGYO KABUSHIKI KAISHA (JP) 1997-06-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050014916-A1 Ruthenium complexes, process for preparation thereof, and processes for producing open-ring polymer of cycloolefins and hydrogenation products thereof by using the complex as catalyst POR, CAD, HRH1 PPM1B 4615/4885KMT2A 1706/4885MEN1 2549/4885
US-20160324970-A1 PROTEIN TRANSDUCTION DOMAINS MIMICS PHAX, GHITM, MAVS PPM1B 3467/4885KMT2A 4710/4885MEN1 947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.