SCHEMBL9696483

SCHEMBL9696483

CC(C)(C)c1ccc(OC(CCCc2ccc(Cl)cc2)C(=O)O)cc1

nearest known ligand 0.81

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 20/20 0.81
PPARG P37231 19/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9614193 0.95 PPARA (0.73) PPARAPPARG
SCHEMBL9614218 0.95 PPARA (0.73) PPARAPPARG
SCHEMBL9696319 0.89 PPARG (0.61) PPARAPPARG
SCHEMBL9858575 0.85 PPARA (0.63) PPARAPPARG
SCHEMBL9696344 0.85 PPARA (0.64) PPARAPPARG
SCHEMBL9696467 0.84 PPARA (0.89) PPARAPPARG
SCHEMBL9696946 0.84 PPARA (0.74) PPARAPPARG
SCHEMBL9696474 0.84 PPARG (0.56) PPARAPPARG
SCHEMBL9614213 0.84 PPARA (0.56) PPARAPPARG
SCHEMBL9697442 0.84 PPARA (0.67) PPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0507238-A1 Optically active carboxylic acids and medicinal preparations containing them Roche Diagnostics GmbH (DE) 1992-10-07 EP disclosed