Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.63 |
| ▸ | PPARG | P37231 | 17/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9613840 | 0.90 | PPARG (0.59) | PPARAPPARGSMN1; SMN2 | |
| SCHEMBL9858489 | 0.90 | PPARG (0.76) | PPARAPPARG | |
| SCHEMBL9614051 | 0.86 | PPARA (0.67) | PPARAPPARG | |
| SCHEMBL9614218 | 0.86 | PPARA (0.73) | PPARAPPARG | |
| SCHEMBL9614193 | 0.86 | PPARA (0.73) | PPARAPPARG | |
| SCHEMBL9696483 | 0.85 | PPARA (0.81) | PPARAPPARG | |
| SCHEMBL9614120 | 0.85 | PPARA (0.66) | PPARAPPARG | |
| SCHEMBL9614013 | 0.85 | PPARA (0.66) | PPARAPPARG | |
| SCHEMBL9696954 | 0.84 | PPARA (0.53) | PPARAPPARGSMN1; SMN2 | |
| SCHEMBL9696806 | 0.83 | PPARA (0.63) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279162-B1 | CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1991-06-19 | — | — | EP | disclosed |
| EP-0279162-A1 | Carbonic acid derivatives, process for their preparation and pharmaceuticals containing them | Roche Diagnostics GmbH (DE) | 1988-08-24 | — | — | EP | disclosed |