Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | HTR2C | P28335 | 4/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.47 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | HTR1D | P28221 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695050 | 0.84 | KDM4E (0.83) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL12874806 | 0.83 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL2159345 | 0.82 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL29387209 | 0.82 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL9695044 | 0.82 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL9696157 | 0.81 | KDM4E (0.89) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL7010093 | 0.80 | KDM4E (0.73) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL9695038 | 0.77 | KDM4E (0.69) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL9697117 | 0.77 | KDM4E (0.69) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL5705100 | 0.77 | KDM4E (0.66) | KDM4EALDH1A1HSD17B10MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169947-A | 3-(1,2,5,6-tetrahydropyridyl)-pyrrolopyridines | PFIZER INC. (US) | 1992-12-08 | — | — | US | claimed |