Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.34 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2349928 | 0.82 | KDM4E (0.44) | GRM4ALDH1A1NR4A2SOS2MAPT | |
| SCHEMBL3119349 | 0.82 | MAP2K3 (0.39) | GRM4NR4A2SOS2IKBKB | |
| SCHEMBL6169100 | 0.77 | PDE3B (0.40) | PDE3BPDE3AALDH1A1PRKCIMAPT | |
| SCHEMBL31523000 | 0.77 | KDM4E (0.43) | PDE3BPDE3AALDH1A1CREBBPPRKCI | |
| SCHEMBL27800797 | 0.77 | PDE3B (0.40) | PDE3BPDE3AALDH1A1CREBBPPRKCI | |
| SCHEMBL20520334 | 0.76 | KDM4E (0.42) | PDE3BPDE3AALDH1A1MAPTGABRP | |
| SCHEMBL31146087 | 0.73 | HSD17B10 (0.38) | ALDH1A1NR4A2SOS2MAPTPTPN11 | |
| SCHEMBL365395 | 0.72 | ALDH1A1 (0.45) | ALDH1A1MAPTL3MBTL1GAAHTT | |
| SCHEMBL3380838 | 0.72 | GRM4 (0.46) | PDE3BPDE3AGRM4ALDH1A1MAPT | |
| SCHEMBL21198626 | 0.72 | HSD17B10 (0.37) | PDE3BPDE3AALDH1A1PTPN11IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149822-A | PREPARATION OF 2,3-DICHLORO-5-ACETYLPYRIDINE | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-22 | — | — | US | disclosed |