Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.47 |
| ▸ | PPARG | P37231 | 13/20 | 0.47 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695333 | 0.89 | PPARA (0.47) | PPARAPPARGCTRCSMN1; SMN2PTGES | |
| SCHEMBL9696452 | 0.89 | PPARG (0.51) | PPARAPPARGCTRCSMN1; SMN2PTGES | |
| SCHEMBL9696319 | 0.87 | PPARG (0.61) | PPARAPPARGCTRCSMN1; SMN2PTGES | |
| SCHEMBL9696474 | 0.85 | PPARG (0.56) | PPARAPPARGCTRCPTGESALOX5 | |
| SCHEMBL9614239 | 0.85 | PPARG (0.63) | PPARAPPARGCTRCPTGESALOX5 | |
| SCHEMBL9696796 | 0.85 | PPARG (0.63) | PPARAPPARGCTRCPTGESALOX5 | |
| SCHEMBL9614213 | 0.83 | PPARA (0.56) | PPARAPPARGCTRCNR1H4 | |
| SCHEMBL9614193 | 0.82 | PPARA (0.73) | PPARAPPARG | |
| SCHEMBL9614218 | 0.82 | PPARA (0.73) | PPARAPPARG | |
| SCHEMBL9695306 | 0.80 | PPARG (0.53) | PPARAPPARGCTRCPTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017435-A1 | OPTICALLY ACTIVE CARBOXYLIC ACIDS AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-15 | — | — | WO | disclosed |
| EP-0507238-A1 | Optically active carboxylic acids and medicinal preparations containing them | Roche Diagnostics GmbH (DE) | 1992-10-07 | — | — | EP | disclosed |