Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2690695 | 0.82 | HDAC8 (0.55) | HDAC8HDAC6ALDH1A1MAPTMAPK1 | |
| SCHEMBL2690696 | 0.82 | HDAC8 (0.55) | HDAC8HDAC6ALDH1A1MAPTMAPK1 | |
| SCHEMBL7024673 | 0.81 | APP (0.58) | ALDH1A1MAPTMAPK1APPMEN1 | |
| SCHEMBL27724705 | 0.81 | HDAC8 (0.56) | HDAC8HDAC6ALDH1A1MAPTMAPK1 | |
| SCHEMBL28989841 | 0.80 | EGFR (0.54) | HDAC8HDAC6ALDH1A1MAPTMAPK1 | |
| SCHEMBL5388256 | 0.80 | CYP3A4 (0.53) | ALDH1A1MAPTMAPK1HPGDAPP | |
| SCHEMBL5388253 | 0.80 | CYP3A4 (0.53) | ALDH1A1MAPTMAPK1HPGDAPP | |
| SCHEMBL11820758 | 0.79 | APP (0.50) | ALDH1A1MAPTMAPK1HPGDAPP | |
| SCHEMBL6794099 | 0.78 | EGFR (0.53) | HDAC8HDAC6ALDH1A1MAPTMAPK1 | |
| SCHEMBL6794103 | 0.78 | EGFR (0.53) | HDAC8HDAC6ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992000547-A1 | POLYMERIC COMPOSITIONS | BRITISH TELECOMMUNICATIONS PUBLIC LIMITED COMPANY (GB) | 1992-01-09 | — | — | WO | disclosed |