Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 7/20 | 0.36 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9488985 | 0.90 | RAD52 (0.54) | RAD52KDM4ELMNACXCR4CXCL12 | |
| SCHEMBL9782959 | 0.81 | RAD52 (0.51) | RAD52KDM4ELMNASIGMAR1SMN1; SMN2 | |
| SCHEMBL11142790 | 0.77 | CXCR4 (0.44) | RAD52KDM4ELMNACXCR4CXCL12 | |
| SCHEMBL9351938 | 0.76 | KDM4E (0.40) | RAD52KDM4ELMNACXCR4CXCL12 | |
| SCHEMBL6493217 | 0.76 | RAD52 (0.59) | RAD52LMNACXCR4CXCL12HRH3 | |
| SCHEMBL6503351 | 0.76 | RAD52 (0.59) | RAD52LMNACXCR4CXCL12HRH3 | |
| SCHEMBL10605493 | 0.76 | SLC2A1 (0.46) | RAD52KDM4ELMNACXCR4CXCL12 | |
| SCHEMBL7947655 | 0.74 | RAD52 (0.58) | RAD52LMNACXCR4CXCL12HRH3 | |
| SCHEMBL20614282 | 0.74 | RAD52 (0.58) | RAD52LMNACXCR4CXCL12HRH3 | |
| SCHEMBL9490794 | 0.73 | TP53 (0.30) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508181-A1 | Hybrid process for preparing a tri-substituted triazine | THE B.F. GOODRICH COMPANY (US) | 1992-10-14 | — | — | EP | claimed |
| EP-0508181-A1 | Hybrid process for preparing a tri-substituted triazine | THE B.F. GOODRICH COMPANY (US) | 1992-10-14 | — | — | EP | disclosed |
| US-5106971-A | Hybrid process for preparing a tri-substituted triazine | THE B. F. GOODRICH COMPANY (US) | 1992-04-21 | — | — | US | disclosed |