Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13508713 | 0.86 | CYP11B1 (0.62) | GRM2LTA4HCYP11B1CYP11B2HTT | |
| SCHEMBL31229158 | 0.85 | CYP11B1 (0.62) | LTA4HCYP11B1CYP11B2HTTSMN1; SMN2 | |
| SCHEMBL10641566 | 0.81 | CYP11B1 (0.45) | GRM2LTA4HCYP11B1CYP11B2HTT | |
| SCHEMBL22533654 | 0.81 | LTA4H (0.45) | GRM2LTA4HCYP11B1CYP11B2HTT | |
| SCHEMBL10468436 | 0.80 | MEN1 (0.64) | GRM2LTA4HCYP11B1CYP11B2TNF | |
| SCHEMBL7834456 | 0.78 | CYP11B1 (0.75) | GRM2CYP11B1CYP11B2HTTSMN1; SMN2 | |
| SCHEMBL18805043 | 0.78 | CYP11B1 (0.75) | GRM2CYP11B1CYP11B2HTTSMN1; SMN2 | |
| SCHEMBL6660983 | 0.77 | HDAC1 (0.62) | LTA4HCYP11B1CYP11B2HTTSMN1; SMN2 | |
| SCHEMBL30932218 | 0.75 | TP53 (0.66) | GRM2CYP11B1CYP11B2HTTSMN1; SMN2 | |
| SCHEMBL9696462 | 0.75 | TP53 (0.66) | GRM2CYP11B1CYP11B2HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006086-A1 | NOVEL 4-PIPERIDINYLCARBONYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-04-16 | — | — | WO | disclosed |