Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8490703 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL9248248 | 0.89 | ALDH1A1 (0.45) | SMN1; SMN2LMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL9245910 | 0.86 | POLB (0.45) | SMN1; SMN2LMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL9371713 | 0.82 | HDAC1 (0.46) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9300884 | 0.81 | POLB (0.47) | SMN1; SMN2LMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL8488725 | 0.80 | MAPT (0.38) | SMN1; SMN2LMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL8488726 | 0.79 | ALDH1A1 (0.37) | SMN1; SMN2LMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL9221651 | 0.78 | TYMS (0.43) | SMN1; SMN2LMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL8485814 | 0.77 | GAA (0.43) | SMN1; SMN2LMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL9299066 | 0.77 | POLB (0.43) | SMN1; SMN2LMNAHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509643-A1 | Anti-cancer compounds | BTG INTERNATIONAL LIMITED (GB) | 1992-10-21 | — | — | EP | disclosed |