Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12879487 | 0.76 | MAPT (0.42) | ESR1ESR2TP53MAPTKDM4E | |
| SCHEMBL20637319 | 0.76 | ESR1 (0.38) | ESR1ESR2TP53MAPTKDM4E | |
| SCHEMBL13089067 | 0.76 | ESR1 (0.38) | ESR1ESR2TP53MAPTKDM4E | |
| SCHEMBL121702 | 0.76 | SMN1; SMN2 (0.37) | MAPTALDH1A1SMN1; SMN2SIGMAR1PKM | |
| Water SCHEMBL28197942 | 0.74 | MAPT (0.41) | ESR1ESR2TP53MAPTKDM4E | |
| SCHEMBL10280463 | 0.73 | TP53 (0.38) | ESR1ESR2TP53MAPTKDM4E | |
| SCHEMBL28218923 | 0.73 | TP53 (0.38) | ESR1ESR2TP53MAPTKDM4E | |
| SCHEMBL3889886 | 0.73 | NR1H2 (0.50) | ESR1ESR2TP53MAPTKDM4E | |
| SCHEMBL10730048 | 0.73 | ESR1 (0.45) | ESR1ESR2TP53MAPTKDM4E | |
| SCHEMBL272095 | 0.73 | NR1H2 (0.40) | ESR1ESR2TP53MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117024-A | Hydrogenation with hydrogen gas of cyanoorganosilane in the presence of a supported cobalt catalyst | DOW CORNING CORPORATION (US) | 1992-05-26 | — | — | US | disclosed |