Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2835919 | 0.91 | USP2 (0.50) | LPAR1LPAR3LPAR2USP2HTT | |
| SCHEMBL11042865 | 0.91 | USP2 (0.50) | LPAR1LPAR3LPAR2USP2HTT | |
| SCHEMBL2839409 | 0.91 | USP2 (0.50) | LPAR1LPAR3LPAR2USP2HTT | |
| SCHEMBL2420872 | 0.91 | USP2 (0.50) | LPAR1LPAR3LPAR2USP2HTT | |
| SCHEMBL17629258 | 0.91 | USP2 (0.50) | LPAR1LPAR3LPAR2USP2HTT | |
| SCHEMBL11572401 | 0.91 | USP2 (0.50) | LPAR1LPAR3LPAR2USP2HTT | |
| SCHEMBL2070625 | 0.89 | TSHR (0.33) | LPAR1LPAR3LPAR2USP2TSHR | |
| SCHEMBL21518237 | 0.82 | PRKD3 (0.42) | LPAR1LPAR3LPAR2USP2TSHR | |
| SCHEMBL11199731 | 0.82 | USP2 (0.42) | LPAR1LPAR3LPAR2USP2HTT | |
| SCHEMBL994359 | 0.82 | LPAR1 (0.50) | LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005788-A1 | NEW PHOSPHONATE DERIVATIVES AS LIPASE AGENTS INHIBITING | NOVO NORDISK A/S (DK) | 1992-04-16 | — | — | WO | claimed |