Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 2/20 | 0.50 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20573193 | 1.00 | LPAR1 (0.50) | LPAR1LPAR3ALDH1A1CNR1CNR2 | |
| SCHEMBL15319711 | 0.95 | ALDH1A1 (0.55) | LPAR1LPAR3ALDH1A1CNR1CNR2 | |
| SCHEMBL21248514 | 0.95 | ALDH1A1 (0.55) | LPAR1LPAR3ALDH1A1CNR1CNR2 | |
| SCHEMBL4300775 | 0.93 | ALDH1A1 (0.52) | LPAR1LPAR3ALDH1A1CNR1CNR2 | |
| SCHEMBL11042865 | 0.89 | USP2 (0.50) | LPAR1LPAR3 | |
| SCHEMBL2839409 | 0.89 | USP2 (0.50) | LPAR1LPAR3 | |
| SCHEMBL17629258 | 0.89 | USP2 (0.50) | LPAR1LPAR3 | |
| SCHEMBL11572401 | 0.89 | USP2 (0.50) | LPAR1LPAR3 | |
| SCHEMBL2835919 | 0.89 | USP2 (0.50) | LPAR1LPAR3 | |
| SCHEMBL2420872 | 0.89 | USP2 (0.50) | LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110268048-B | Generation of atrial and ventricular cardiomyocyte lineages from human pluripotent stem cells | 大学健康网络 | 2024-07-09 | — | — | CN | disclosed |
| CN-117794951-A | Claudin 18.2T cell antigen conjugate and application thereof | 特拉姆维拉免疫美国有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-111479925-B | T cell-antigen conjugates with Y182T mutations and methods and uses thereof | 麦克马斯特大学 | 2024-03-08 | — | — | CN | disclosed |
| CN-117480249-A | Stem cells comprising unrearranged T Cell Receptor (TCR) loci and methods of use thereof | 桑尼布鲁克研究所 | 2024-01-30 | — | — | CN | disclosed |
| CN-117396513-A | Combination therapy for the treatment of cancer | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-116744948-A | Cells comprising T cell antigen conjugates and uses thereof | 麦克马斯特大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-116333108-A | Antibodies to amyloid beta | 英属哥伦比亚大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-114651068-A | Chimeric co-stimulatory receptors and methods and uses thereof | 麦克马斯特大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-1954073-B | Modified Bouganin proteins, cytotoxins and methods and uses thereof | MERCK PATENT GMBH | 2013-01-16 | — | — | CN | disclosed |
| EP-2453918-A2 | RSV F PROTEIN COMPOSITIONS AND METHODS FOR MAKING SAME | Novartis AG (CH) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011008974-A2 | RSV F PROTEIN COMPOSITIONS AND METHODS FOR MAKING SAME | NOVARTIS AG (CH) | 2011-01-20 | — | — | WO | disclosed |
| CN-1954073-A | Modified Bouganin proteins, cytotoxins and methods and uses thereof | MERCK PATENT GMBH (DE) | 2007-04-25 | — | — | CN | disclosed |
| EP-1261379-A2 | GENETIC MODIFICATION OF THE LUNG AS A PORTAL FOR GENE DELIVERY | GENZYME CORPORATION (US) | 2002-12-04 | — | — | EP | disclosed |
| WO-2002055110-A2 | METHODS FOR TREATING BLOOD COAGULATION DISORDERS | GENZYME CORP (US) | 2002-07-18 | — | — | WO | disclosed |
| WO-2002009770-A1 | USE OF RAPAMYCIN TO INHIBIT IMMUNE RESPONSE AND INDUCE TOLERANCE TO GENE THERAPY VECTOR AND ENCODED TRANSGENE PRODUCTS | GENZYME CORPORATION (US) | 2002-02-07 | — | — | WO | disclosed |
| WO-2001060414-A2 | GENETIC MODIFICATION OF THE LUNG AS A PORTAL FOR GENE DELIVERY | GENZYME CORPORATION (US) | 2001-08-23 | — | — | WO | disclosed |