Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699467 | 0.91 | NR1D1 (0.32) | — | |
| SCHEMBL9387011 | 0.86 | PARP1 (0.33) | — | |
| SCHEMBL9382009 | 0.86 | PARP1 (0.33) | — | |
| SCHEMBL9385456 | 0.86 | PARP1 (0.33) | — | |
| SCHEMBL9382084 | 0.83 | PARP1 (0.30) | — | |
| SCHEMBL9696883 | 0.82 | — | — | |
| SCHEMBL9194033 | 0.82 | — | — | |
| SCHEMBL9382330 | 0.81 | PARP1 (0.31) | LMNAMAPK1RAB9A | |
| SCHEMBL9697616 | 0.81 | — | — | |
| SCHEMBL9383355 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002521-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-20 | — | — | WO | disclosed |