Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | GBA1 | P04062 | 2/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11813903 | 0.87 | MAPT (0.83) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL29609022 | 0.79 | MAPT (0.93) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL6237782 | 0.79 | MAPT (0.93) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL10429487 | 0.78 | MAPT (0.64) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL30260564 | 0.78 | LRRK2 (0.56) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL3191755 | 0.77 | MAPT (0.69) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL20004385 | 0.77 | EGFR (0.71) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL9483332 | 0.77 | NPSR1 (0.54) | MAPTALDH1A1SMN1; SMN2KMT2ANPSR1 | |
| SCHEMBL20355106 | 0.76 | HTT (0.60) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL16928184 | 0.76 | MAPT (0.65) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116957-A | REACTIVE AZO DYESTUFFS HAVING A FLUOROTRIAZINE GROUP AND IMPROVED FIXATION PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-05-26 | — | — | US | disclosed |