Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 7/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 6/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.42 |
| ▸ | GABRE | P78334 | 2/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9697797 | 0.89 | SLC1A2 (0.40) | SLC1A2SLC1A3SLC1A1GABRPGABRD | |
| SCHEMBL4082420 | 0.82 | SLC1A1 (0.48) | SLC1A2SLC1A3SLC1A1GRIK1GRIK2 | |
| SCHEMBL10587255 | 0.78 | GABRR1 (0.41) | SLC1A2SLC1A3SLC1A1GRIK1GRIK2 | |
| SCHEMBL18556768 | 0.75 | CA2 (0.56) | SLC1A2SLC1A3SLC1A1GABRPGABRD | |
| SCHEMBL2989325 | 0.74 | SLC1A3 (0.50) | SLC1A2SLC1A3SLC1A1CHRM1AKR1A1 | |
| SCHEMBL4269623 | 0.74 | FOLH1 (0.56) | SLC1A2SLC1A3SLC1A1GRIK1GRIK2 | |
| Methane SCHEMBL28186622 | 0.72 | FOLH1 (0.54) | SLC1A2SLC1A3SLC1A1GRIK1GRIK2 | |
| SCHEMBL5696058 | 0.72 | FOLH1 (0.55) | SLC1A2SLC1A3SLC1A1GABRPGABRD | |
| Butane SCHEMBL27527358 | 0.72 | FOLH1 (0.48) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL10485819 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5099063-A | 3-(1-aminoalkylphosphinyl)-(2-substituted)propionic acids | MERCK & CO., INC. (US) | 1992-03-24 | — | — | US | disclosed |