⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686297 | 0.79 | CA1 (0.31) | — | |
| SCHEMBL11327108 | 0.75 | — | — | |
| SCHEMBL346877 | 0.64 | — | — | |
| SCHEMBL14119779 | 0.64 | — | — | |
| SCHEMBL9697898 | 0.60 | — | — | |
| SCHEMBL136645 | 0.59 | — | — | |
| SCHEMBL12152692 | 0.58 | — | — | |
| SCHEMBL2545205 | 0.57 | MAP3K14 (0.39) | — | |
| SCHEMBL11996425 | 0.57 | MAP3K14 (0.39) | — | |
| Hydrochloric Acid SCHEMBL15546474 | 0.55 | MAP3K14 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5136050-A | Process for resolving amino acids using substituted lactones | ROUSSEL UCLAF (FR) | 1992-08-04 | — | — | US | claimed |
| EP-0030505-B1 | LACTONES SUBSTITUTED BY AN AMINO-ACID RESIDUE, THEIR PREPARATION AND THEIR USE IN THE SEPARATION OF SAID LACTONES OR AMINO ACIDS | ROUSSEL-UCLAF (FR) | 1985-07-24 | — | — | EP | claimed |
| EP-0030505-A1 | Lactones substituted by an amino-acid residue, their preparation and their use in the separation of said lactones or amino acids | ROUSSEL-UCLAF (FR) | 1981-06-17 | — | — | EP | claimed |
| EP-0004493-B1 | ETHERS WHOSE ORGANIC MOIETIES HAVE ASYMMETRIC ATOMS, METHODS FOR THEIR PREPARATION AND THEIR USE FOR THE RESOLUTION OF ALCOHOLS, PHENOLS OR CERTAIN COMPOUNDS WITH A LACTONE STRUCTURE | ROUSSEL-UCLAF (FR) | 1981-05-06 | — | — | EP | claimed |
| EP-0004493-A1 | Ethers whose organic moieties have asymmetric atoms, methods for their preparation and their use for the resolution of alcohols, phenols or certain compounds with a lactone structure | ROUSSEL-UCLAF (FR) | 1979-10-03 | — | — | EP | claimed |
| US-5136050-A | Process for resolving amino acids using substituted lactones | ROUSSEL UCLAF (FR) | 1992-08-04 | — | — | US | disclosed |
| US-4935532-A | Hemiacetals | ROUSSEL UCLAF (FR) | 1990-06-19 | — | — | US | disclosed |
| US-4788305-A | HETEROCYCLIC HEMIACETALS | ROUSSEL UCLAF (FR) | 1988-11-29 | — | — | US | disclosed |
| US-4720556-A | 3-oxabicyclo-(3,1,0)-hexan-2-ones | ROUSSEL UCLAF (FR) | 1988-01-19 | — | — | US | disclosed |
| US-4701542-A | Resolution of hemiacetals and alcohols | ROUSSEL UCLAF (FR) | 1987-10-20 | — | — | US | disclosed |
| EP-0082049-B1 | ETHERS WITH CHIRAL ATOMS IN THE ORGANIC REST GROUPS, THEIR PREPARATION, THEIR USE IN THE RESOLUTION OF ALCOHOLS OR OF CERTAIN HEMIACETALS, AND COMPOUNDS SO RESOLVED | ROUSSEL-UCLAF (FR) | 1987-07-29 | — | — | EP | disclosed |
| US-4658043-A | Ethers of pantolactone | ROUSSEL UCLAF (FR) | 1987-04-14 | — | — | US | disclosed |
| EP-0030505-B1 | LACTONES SUBSTITUTED BY AN AMINO-ACID RESIDUE, THEIR PREPARATION AND THEIR USE IN THE SEPARATION OF SAID LACTONES OR AMINO ACIDS | ROUSSEL-UCLAF (FR) | 1985-07-24 | — | — | EP | disclosed |
| EP-0082049-A2 | Ethers with chiral atoms in the organic rest groups, their preparation, their use in the resolution of alcohols or of certain hemiacetals, and compounds so resolved | ROUSSEL-UCLAF (FR) | 1983-06-22 | — | — | EP | disclosed |
| US-4374257-A | Novel ethers containing a lactone group and a chiral atom | ROUSSEL UCLAF (FR) | 1983-02-15 | — | — | US | disclosed |
| US-4350637-A | STEREOISOMERS, RESOLUTION | ROUSSEL UCLAF (FR) | 1982-09-21 | — | — | US | disclosed |
| EP-0030505-A1 | Lactones substituted by an amino-acid residue, their preparation and their use in the separation of said lactones or amino acids | ROUSSEL-UCLAF (FR) | 1981-06-17 | — | — | EP | disclosed |
| EP-0004493-B1 | ETHERS WHOSE ORGANIC MOIETIES HAVE ASYMMETRIC ATOMS, METHODS FOR THEIR PREPARATION AND THEIR USE FOR THE RESOLUTION OF ALCOHOLS, PHENOLS OR CERTAIN COMPOUNDS WITH A LACTONE STRUCTURE | ROUSSEL-UCLAF (FR) | 1981-05-06 | — | — | EP | disclosed |
| US-4265817-A | Novel chiral ethers and their use in resolution of alcohols and phenols | ROUSSEL UCLAF (FR) | 1981-05-05 | — | — | US | disclosed |
| EP-0004493-A1 | Ethers whose organic moieties have asymmetric atoms, methods for their preparation and their use for the resolution of alcohols, phenols or certain compounds with a lactone structure | ROUSSEL-UCLAF (FR) | 1979-10-03 | — | — | EP | disclosed |