SCHEMBL2545205

SCHEMBL2545205

O=C1NC(=O)[C@H]2C1=C1CC[C@H]2C1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAP3K14 Q99558 1/20 0.39
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11996425 1.00 MAP3K14 (0.39) MAP3K14MAPT
Hydrochloric Acid SCHEMBL15546671 0.98 MAP3K14 (0.38) MAP3K14MAPT
SCHEMBL4591427 0.90 MAPT (0.38) MAP3K14MAPT
SCHEMBL3489916 0.67 MAP3K14 (0.33) MAP3K14
SCHEMBL14119779 0.64
SCHEMBL346877 0.64
SCHEMBL7443364 0.62
SCHEMBL10470252 0.59
SCHEMBL748562 0.54
SCHEMBL7640738 0.54 MAPT (0.65) MAP3K14MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3057966-B1 PROCESS FOR THE INDUSTRIAL SYNTHESIS OF LURASIDONE PROCOS SPA (IT) 2017-07-26 EP claimed
US-9518047-B2 Process for the industrial synthesis of lurasidone PROCOS S.P.A. (IT) 2016-12-13 US claimed
EP-3057966-A1 PROCESS FOR THE INDUSTRIAL SYNTHESIS OF LURASIDONE Procos S.p.A. (IT) 2016-08-24 EP claimed
US-20160237077-A1 PROCESS FOR THE INDUSTRIAL SYNTHESIS OF LURASIDONE PROCOS S.P.A. (IT) 2016-08-18 US claimed
WO-2015056205-A1 PROCESS FOR THE INDUSTRIAL SYNTHESIS OF LURASIDONE PROCOS S.P.A. (IT) 2015-04-23 WO claimed
EP-3057966-B1 PROCESS FOR THE INDUSTRIAL SYNTHESIS OF LURASIDONE PROCOS SPA (IT) 2017-07-26 EP disclosed
US-9518047-B2 Process for the industrial synthesis of lurasidone PROCOS S.P.A. (IT) 2016-12-13 US disclosed
EP-2563790-B1 A PROCESS OF A QUATERNARY AMMONIUM SALT SUMITOMO DAINIPPON PHARMA CO LTD (JP) 2016-09-14 EP disclosed
EP-3057966-A1 PROCESS FOR THE INDUSTRIAL SYNTHESIS OF LURASIDONE Procos S.p.A. (IT) 2016-08-24 EP disclosed
US-20160237077-A1 PROCESS FOR THE INDUSTRIAL SYNTHESIS OF LURASIDONE PROCOS S.P.A. (IT) 2016-08-18 US disclosed
US-9309255-B2 Process of a quaternary ammonium salt SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2016-04-12 US disclosed
WO-2015056205-A1 PROCESS FOR THE INDUSTRIAL SYNTHESIS OF LURASIDONE PROCOS S.P.A. (IT) 2015-04-23 WO disclosed
US-20150087830-A1 PROCESS OF A QUATERNARY AMMONIUM SALT SUMITOMO DAINIPPON PHARMA CO., LTD 2015-03-26 US disclosed
US-8921551-B2 Process of a quaternary ammonium salt SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2014-12-30 US disclosed
EP-2563791-B1 A PROCESS OF A QUATERNARY AMMONIUM SALT USING PHOSPHATE SUMITOMO DAINIPPON PHARMA CO LTD (JP) 2014-12-24 EP disclosed
US-20140256939-A1 PROCESS OF PREPARING A QUATERNARY AMMONIUM SALT USING PHOSPHATE DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2014-09-11 US disclosed
US-20140031548-A1 PROCESS OF A QUATERNARY AMMONIUM SALT USING PHOSPHATE SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2014-01-30 US disclosed
US-8586737-B2 Process of a quaternary ammonium salt using phosphate DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2013-11-19 US disclosed
US-20110263847-A1 PROCESS OF A QUATERNARY AMMONIUM SALT DAINIPPON SUMITOMO PHARMA CO, LTD. (JP) 2011-10-27 US disclosed
US-20110263848-A1 PROCESS OF A QUATERNARY AMMONIUM SALT USING PHOSPHATE DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2011-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150087830-A1 PROCESS OF A QUATERNARY AMMONIUM SALT KAT5, ATP1B2, QARS1 MAP3K14 2513/4885MAPT 2417/4885
US-20140031548-A1 PROCESS OF A QUATERNARY AMMONIUM SALT USING PHOSPHATE PHPT1, SLC34A2, SLC34A3 MAP3K14 2752/4885MAPT 2969/4885
US-20110263847-A1 PROCESS OF A QUATERNARY AMMONIUM SALT KAT5, ATP1B2, QARS1 MAP3K14 2513/4885MAPT 2417/4885
US-20110263848-A1 PROCESS OF A QUATERNARY AMMONIUM SALT USING PHOSPHATE PHPT1, SLC34A2, SLC34A3 MAP3K14 2752/4885MAPT 2969/4885
US-20160237077-A1 PROCESS FOR THE INDUSTRIAL SYNTHESIS OF LURASIDONE REN, DCXR, ADRA1D MAP3K14 2042/4885MAPT 1466/4885
US-20140256939-A1 PROCESS OF PREPARING A QUATERNARY AMMONIUM SALT USING PHOSPHATE AGPS, SLC34A3, SLC34A1 MAP3K14 2431/4885MAPT 3084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.