Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9697558 | 0.99 | SMN1; SMN2 (0.50) | SMN1; SMN2USP2ALDH1A1ITGB3ITGAV | |
| SCHEMBL9696030 | 0.84 | TNKS (0.42) | SMN1; SMN2USP2ALDH1A1NOD1NOD2 | |
| SCHEMBL9695958 | 0.82 | TSHR (0.60) | SMN1; SMN2USP2ALDH1A1NOD1NOD2 | |
| SCHEMBL9697931 | 0.74 | NR3C2 (0.44) | MEN1KMT2AHDAC6 | |
| SCHEMBL6868621 | 0.71 | SMN1; SMN2 (0.58) | SMN1; SMN2USP2ALDH1A1NPC1RAB9A | |
| SCHEMBL5610013 | 0.71 | SMN1; SMN2 (0.68) | SMN1; SMN2USP2ALDH1A1NPC1RAB9A | |
| SCHEMBL9695968 | 0.69 | SMN1; SMN2 (0.56) | SMN1; SMN2USP2ALDH1A1NPC1RAB9A | |
| SCHEMBL10644455 | 0.69 | MCHR1 (0.55) | ALDH1A1TSHRHDAC1HDAC6 | |
| SCHEMBL5608402 | 0.66 | SMN1; SMN2 (0.61) | SMN1; SMN2USP2ALDH1A1NPC1RAB9A | |
| SCHEMBL9695933 | 0.66 | TSHR (0.48) | SMN1; SMN2USP2ALDH1A1NOD1NOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149700-A | Antiarrhythmic agent | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-22 | — | — | US | claimed |
| WO-1991018904-A1 | SUBSTITUTED ARYLSULFONAMIDES AND BENZAMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-12-12 | — | — | WO | claimed |
| US-5149700-A | Antiarrhythmic agent | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |
| WO-1991018904-A1 | SUBSTITUTED ARYLSULFONAMIDES AND BENZAMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-12-12 | — | — | WO | disclosed |