Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KRAS | P01116 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23303404 | 0.88 | BCHE (0.70) | BCHETDP1PKMDDAH1GAA | |
| SCHEMBL23336458 | 0.85 | BCHE (0.66) | BCHETDP1PKMDDAH1GAA | |
| SCHEMBL711939 | 0.85 | TDP1 (0.70) | BCHETDP1PKMDDAH1GAA | |
| SCHEMBL1333203 | 0.82 | BCHE (0.82) | BCHETDP1PKMDDAH1GAA | |
| SCHEMBL708642 | 0.82 | TDP1 (0.63) | BCHETDP1PKMDDAH1GAA | |
| Hydrochloric Acid SCHEMBL709917 | 0.82 | TDP1 (0.71) | BCHETDP1PKMDDAH1GAA | |
| Hydrochloric Acid SCHEMBL708641 | 0.82 | TDP1 (0.67) | BCHETDP1PKMDDAH1GAA | |
| Hydrochloric Acid SCHEMBL709918 | 0.82 | TDP1 (0.67) | BCHETDP1PKMDDAH1GAA | |
| Hydrochloric Acid SCHEMBL708640 | 0.82 | TDP1 (0.71) | BCHETDP1PKMDDAH1GAA | |
| SCHEMBL8509650 | 0.80 | TDP1 (0.55) | BCHETDP1PKMGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149700-A | Antiarrhythmic agent | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |
| WO-1991018904-A1 | SUBSTITUTED ARYLSULFONAMIDES AND BENZAMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-12-12 | — | — | WO | disclosed |