Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 4/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.43 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216843 | 0.89 | KDM4E (0.55) | KDM4ENPC1USP2ALDH1A1GLA | |
| SCHEMBL8488865 | 0.84 | KDM4E (0.57) | KDM4ENPC1USP2ALDH1A1GLA | |
| SCHEMBL8529995 | 0.79 | KDM4E (0.66) | KDM4ENPC1USP2ALDH1A1GLA | |
| SCHEMBL7420764 | 0.79 | KDM4E (0.54) | KDM4ENPC1USP2ALDH1A1GLA | |
| SCHEMBL27496027 | 0.77 | KDM4E (0.55) | KDM4ENPC1USP2ALDH1A1GLA | |
| SCHEMBL20327023 | 0.76 | KDM4E (0.58) | KDM4ENPC1USP2ALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL5734972 | 0.74 | KDM4E (0.46) | KDM4ENPC1USP2ALDH1A1GLA | |
| SCHEMBL9298476 | 0.73 | KDM4E (0.58) | KDM4ENPC1USP2ALDH1A1GLA | |
| SCHEMBL20327033 | 0.73 | KDM4E (0.58) | KDM4ENPC1USP2ALDH1A1GLA | |
| SCHEMBL9698003 | 0.72 | KDM4E (0.53) | KDM4ENPC1USP2ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509643-A1 | Anti-cancer compounds | BTG INTERNATIONAL LIMITED (GB) | 1992-10-21 | — | — | EP | disclosed |
| WO-1992016512-A1 | ANTI-CANCER COMPOUNDS | BRITISH TECHNOLOGY GROUP PLC (GB) | 1992-10-01 | — | — | WO | disclosed |