SCHEMBL9698166

SCHEMBL9698166

CCCc1cnccc1C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 19/20 0.55
KDM6B O15054 10/20 0.55
KDM4D Q6B0I6 4/20 0.50
KDM4E B2RXH2 2/20 0.50
KDM4A O75164 2/20 0.50
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
MAPT P10636 1/20 0.50
THRB P10828 1/20 0.50
KMT2A Q03164 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
KDM5A P29375 2/20 0.43
KDM5B Q9UGL1 2/20 0.43
EGLN3 Q9H6Z9 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30100778 1.00 KDM4C (0.55) KDM4CKDM6BKDM4DKDM4EKDM4A
Hydrochloric Acid SCHEMBL28467486 0.98 KDM4C (0.54) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL11683254 0.90 KDM4C (0.57) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL27449213 0.88 KDM4C (0.56) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL115648 0.87 KDM4C (0.56) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL30100781 0.87 KDM4C (0.56) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL3122447 0.87 KDM4C (0.55) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL11514920 0.86 KDM4C (0.44) KDM4CKDM6BKDM4DKDM4EKDM4A
SCHEMBL258369 0.86 KDM4C (0.51) KDM4CKDM6BKDM4DKDM4EKDM4A
Hydrochloric Acid SCHEMBL1026385 0.85 KDM4C (0.54) KDM4CKDM6BKDM4DKDM4EKDM4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1691610-B1 METHOD FOR MODIFYING THE BEHAVIOUR OF THRIPS WITH PYRIDINE DERIVATIVES NZ INST PLANT & FOOD RES LTD (NZ) 2016-03-09 EP claimed
US-20230128402-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF THE TRUSTEES OF PRINCETON UNIVERSITY 2023-04-27 US disclosed
US-20230128402-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF THE TRUSTEES OF PRINCETON UNIVERSITY 2023-04-27 US disclosed
US-20230128402-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF THE TRUSTEES OF PRINCETON UNIVERSITY 2023-04-27 US disclosed
EP-4093400-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF The Trustees of Princeton University (US) 2022-11-30 EP disclosed
WO-2021151062-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF THE TRUSTEES OF PRINCETON UNIVERISTY (US) 2021-07-29 WO disclosed
WO-2014100463-A1 HISTONE DEMETHYLASE INHIBITORS Quanticel Pharmaceuticals, Inc. (US) 2014-06-26 WO disclosed
WO-2014100818-A1 HISTONE DEMETHYLASE INHIBITORS Quanticel Pharmaceuticals, Inc. (US) 2014-06-26 WO disclosed
WO-1992001688-A1 QUINUCLIDINE DERIVATIVES PFIZER INC. (US) 1992-02-06 WO disclosed
US-4046768-A 1-Thiazolyl-5-pyridylcarbonyloxyimidazolidinones VELSICOL CHEMICAL CORPORATION (US) 1977-09-06 US disclosed
US-4045446-A 1-Benzothiazolyl-5-pyridylcarbonyloxyimidazolidinones VELSICOL CHEMICAL CORPORATION (US) 1977-08-30 US disclosed
US-4033753-A HERICIDES VELSICOL CHEMICAL CORPORATION (US) 1977-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230128402-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF PAH, ALDH2, IDH2 KDM4C 1712/4885KDM6B 1330/4885KDM4D 2730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.