Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 19/20 | 0.56 |
| ▸ | KDM6B | O15054 | 7/20 | 0.56 |
| ▸ | KDM4D | Q6B0I6 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | KDM4A | O75164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30100781 | 1.00 | KDM4C (0.56) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| Hydrochloric Acid SCHEMBL1026385 | 0.98 | KDM4C (0.54) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL30100778 | 0.87 | KDM4C (0.55) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL9698166 | 0.87 | KDM4C (0.55) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| Hydrochloric Acid SCHEMBL28467486 | 0.85 | KDM4C (0.54) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL11236770 | 0.84 | KDM4C (0.44) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL123203 | 0.84 | KDM4C (0.51) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL31132789 | 0.84 | KDM4C (0.55) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL31132830 | 0.84 | KDM4C (0.55) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL30465694 | 0.84 | KDM4C (0.51) | KDM4CKDM6BKDM4DKDM4EKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116944494-A | MOF-derived multi-element rare earth-based composite wave-absorbing material and preparation method thereof | 中国科学院赣江创新研究院 | 2023-10-27 | — | — | CN | claimed |
| CN-116944505-A | MOF structure-based composite wave-absorbing material and preparation method and application thereof | 中国科学院赣江创新研究院 | 2023-10-27 | — | — | CN | claimed |
| US-20250129046-A1 | TETRAHYDROQUINOLINO DERIVATIVES FOR THE TREATMENT OF METASTATIC AND CHEMORESISTANT CANCERS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2025-04-24 | — | — | US | disclosed |
| CN-112638881-B | Tetrahydroquinoline derivatives for the treatment of metastatic and chemotherapy-resistant cancers | 普林斯顿大学托管委员会 | 2025-01-07 | — | — | CN | disclosed |
| US-12162855-B2 | Tetrahydroquinolino derivatives for the treatment of metastatic and chemoresistant cancers | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2024-12-10 | — | — | US | disclosed |
| US-20240343709-A1 | SUBSTITUTED HETEROCYCLES AS ALDEHYDE DEHYDROGENASE INHIBITORS | THE TRUSTEES OF PRINCETON UNIVERSITY | 2024-10-17 | — | — | US | disclosed |
| US-12054475-B2 | Substituted heterocycles as aldehyde dehydrogenase inhibitors | KAYOTHERA INC. (US) | 2024-08-06 | — | — | US | disclosed |
| CN-118005944-A | Antibacterial metal organic framework composite material and preparation method and application thereof | 中国科学院赣江创新研究院 | 2024-05-10 | — | — | CN | disclosed |
| US-20240132469-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KAYOTHERA INC. (US) | 2024-04-25 | — | — | US | disclosed |
| CN-117897370-A | Heterocyclic compounds and their use | 凯悦施那有限公司 | 2024-04-16 | — | — | CN | disclosed |
| EP-4326696-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | Kayothera Inc. (US) | 2024-02-28 | — | — | EP | disclosed |
| EP-0300725-B1 | Tetrahydroisoquinolin-2-yl derivatives as thromboxane A2 antagonists | SMITH KLINE FRENCH LAB (GB) | 1994-06-22 | — | — | EP | disclosed |
| CN-1063015-A | Safe herbicidal sulfonamide compositions | MONSANTO CO (US) | 1992-07-29 | — | — | CN | disclosed |
| CN-1061322-A | The safe of benzoic acid derivative class weed killer herbicide | MONSANTO CO (US) | 1992-05-27 | — | — | CN | disclosed |
| CN-1052768-A | The safe handling of imidazolidinone weedicide | MONSANTO CO (US) | 1991-07-10 | — | — | CN | disclosed |
| CN-1039949-A | The protection of benzoic acid derivative class weed killer herbicide | MONSANTO CO (US) | 1990-02-28 | — | — | CN | disclosed |
| US-4866076-A | THROMBOXANE ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-09-12 | — | — | US | disclosed |
| EP-0300725-A1 | Tetrahydroisoquinolin-2-yl derivatives as thromboxane A2 antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-01-25 | — | — | EP | disclosed |
| US-4675320-A | INHIBIT GROWTH OF MICROORGANISMS | RIKER LABORATORIES, INC. (US) | 1987-06-23 | — | — | US | disclosed |
| US-4526896-A | Microbiocides | RIKER LABORATORIES, INC. (US) | 1985-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240343709-A1 | SUBSTITUTED HETEROCYCLES AS ALDEHYDE DEHYDROGENASE INHIBITORS | ALDH3A1, ALDH2, ALDH1A2 | KDM4C 1147/4885KDM6B 996/4885KDM4D 1951/4885 |
| US-12054475-B2 | Substituted heterocycles as aldehyde dehydrogenase inhibitors | ALDH3A1, ALDH2, ALDH1A2 | KDM4C 1147/4885KDM6B 996/4885KDM4D 1951/4885 |
| US-20250129046-A1 | TETRAHYDROQUINOLINO DERIVATIVES FOR THE TREATMENT OF METASTATIC AND CHEMORESISTANT CANCERS | ALDH3A1, ALDH1A1, ALDH2 | KDM4C 1977/4885KDM6B 1883/4885KDM4D 2614/4885 |
| US-20240132469-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | CYP11B2, ALDH2, PDK1 | KDM4C 1652/4885KDM6B 998/4885KDM4D 2472/4885 |
| US-12162855-B2 | Tetrahydroquinolino derivatives for the treatment of metastatic and chemoresistant cancers | ALDH3A1, ALDH2, ALDH1A1 | KDM4C 1964/4885KDM6B 2140/4885KDM4D 2962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.