Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 12/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 12/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531952 | 0.98 | AGTR1 (0.47) | AGTR1AGTR2PPARG | |
| SCHEMBL9527886 | 0.94 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9530272 | 0.91 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9527108 | 0.89 | AGTR1 (0.46) | AGTR1AGTR2PPARG | |
| SCHEMBL9529791 | 0.89 | AGTR1 (0.36) | AGTR1AGTR2PPARG | |
| SCHEMBL9529963 | 0.88 | AGTR1 (0.34) | AGTR1AGTR2PPARG | |
| SCHEMBL9552383 | 0.88 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9529003 | 0.88 | AGTR1 (0.34) | AGTR1AGTR2PPARG | |
| SCHEMBL9527802 | 0.87 | AGTR1 (0.43) | AGTR1AGTR2PPARG | |
| SCHEMBL6007962 | 0.87 | AGTR1 (0.54) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098920-A | Hypotensive agents and treatment of congestive heart failure | G. D. SEARLE & CO. (US) | 1992-03-24 | — | — | US | disclosed |