Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 8/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.63 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.63 |
| ▸ | HRH1 | P35367 | 2/20 | 0.60 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.60 |
| ▸ | EED | O75530 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | MLNR | O43193 | 1/20 | 0.60 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.60 |
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | HLA-A | P04439 | 1/20 | 0.60 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | LCK | P06239 | 1/20 | 0.60 |
| ▸ | FYN | P06241 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10506180 | 0.89 | SSTR5 (0.67) | SSTR5KCNH2NR4A2HRH1HRH4 | |
| SCHEMBL1153444 | 0.87 | SSTR5 (0.62) | SSTR5KCNH2NR4A2HRH1HRH4 | |
| SCHEMBL11478983 | 0.87 | SSTR5 (0.79) | SSTR5KCNH2NR4A2HRH1HRH4 | |
| SCHEMBL1152912 | 0.85 | SSTR5 (0.64) | SSTR5KCNH2NR4A2HRH1HRH4 | |
| SCHEMBL9535099 | 0.85 | SSTR5 (0.46) | SSTR5KCNH2NR4A2HRH1HRH4 | |
| SCHEMBL10751380 | 0.85 | SSTR5 (0.82) | SSTR5KCNH2NR4A2HRH1HRH4 | |
| SCHEMBL11478841 | 0.85 | SSTR5 (0.68) | SSTR5KCNH2NR4A2HRH1HRH4 | |
| SCHEMBL1152741 | 0.85 | SSTR5 (0.63) | SSTR5KCNH2NR4A2HRH1HRH4 | |
| SCHEMBL1151815 | 0.85 | SSTR5 (0.70) | SSTR5KCNH2NR4A2HRH1HRH4 | |
| Water SCHEMBL9698311 | 0.84 | SSTR5 (0.57) | SSTR5KCNH2NR4A2HRH1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE33833-E | Intermediates for antihistamines, antiserotonine agents | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-02-25 | — | — | US | disclosed |
| US-4820822-A | ANTIHISTAMINE, ANTISEROTONINE AGENTS | JANSSEN PHARMACEUTICA (BE) | 1989-04-11 | — | — | US | disclosed |
| EP-0099139-B1 | NOVEL N-(BICYCLIC HETEROCYCLYL)-4-PIPERIDINAMINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1987-02-11 | — | — | EP | disclosed |