Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 7/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 3/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.30 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1907489 | 0.86 | PRCP (0.34) | CCR2PRCPDPP7CYP1A2 | |
| SCHEMBL9340449 | 0.76 | CCR2 (0.35) | CCR2CCR1CCR5CXCR4PRCP | |
| SCHEMBL21191731 | 0.76 | CYP1A2 (0.36) | CCR2CCR1CCR5CXCR4PRCP | |
| SCHEMBL8471413 | 0.74 | CCR2 (0.33) | CCR2CYP1A2 | |
| SCHEMBL8283621 | 0.74 | CCR2 (0.33) | CCR2CYP1A2 | |
| SCHEMBL21191705 | 0.73 | CCR2 (0.37) | CCR2CCR1CCR5CXCR4PRCP | |
| SCHEMBL22023884 | 0.73 | CYP1A2 (0.34) | CCR2CCR1CCR5CXCR4CYP1A2 | |
| SCHEMBL26653572 | 0.73 | CYP1A2 (0.34) | CCR2CCR1CCR5CXCR4CYP1A2 | |
| Hydrochloric Acid SCHEMBL9698143 | 0.73 | KDM4E (0.34) | CCR2CYP1A2 | |
| SCHEMBL23634135 | 0.71 | CCR2 (0.38) | CCR2CCR1CCR5CXCR4PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992003415-A1 | PROTEIN KINASE C MODULATORS | NOVA PHARMACEUTICAL CORPORATION (US) | 1992-03-05 | — | — | WO | disclosed |