Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.72 |
| ▸ | CNR1 | P21554 | 10/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.56 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.56 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.55 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4108174 | 1.00 | CNR2 (0.72) | CNR2CNR1TSHRLTB4RLTB4R2 | |
| SCHEMBL4113024 | 1.00 | CNR2 (0.72) | CNR2CNR1TSHRLTB4RLTB4R2 | |
| SCHEMBL4109243 | 0.84 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL4110899 | 0.84 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL4115441 | 0.84 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL9698367 | 0.83 | CNR2 (0.62) | CNR2CNR1TSHRMEN1TP53 | |
| SCHEMBL25168636 | 0.83 | LTB4R (0.77) | LTB4RLTB4R2CYSLTR2CYSLTR1MEN1 | |
| SCHEMBL4109823 | 0.82 | CNR2 (0.72) | CNR2CNR1TSHRMEN1TP53 | |
| SCHEMBL3950873 | 0.82 | CNR2 (0.57) | CNR2CNR1TSHRCYSLTR2CYSLTR1 | |
| SCHEMBL4120040 | 0.82 | CNR2 (0.72) | CNR2CNR1TSHRMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090043129-A1 | POTENT AND SELECTIVE LIGANDS OF CANNABINOID RECEPTORS | UNIVERSITA DEGLI STUDI DI SIENA (IT) | 2009-02-12 | — | — | US | claimed |
| EP-1846364-A1 | NEW POTENT AND SELECTIVE LIGANDS OF CANNABINOID RECEPTORS | Universita' Degli Studi di Siena (IT) | 2007-10-24 | — | — | EP | claimed |
| WO-2006080040-A1 | NEW POTENT AND SELECTIVE LIGANDS OF CANNABINOID RECEPTORS | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2006-08-03 | — | — | WO | claimed |
| US-20090043129-A1 | POTENT AND SELECTIVE LIGANDS OF CANNABINOID RECEPTORS | UNIVERSITA DEGLI STUDI DI SIENA (IT) | 2009-02-12 | — | — | US | disclosed |
| EP-1846364-A1 | NEW POTENT AND SELECTIVE LIGANDS OF CANNABINOID RECEPTORS | Universita' Degli Studi di Siena (IT) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006080040-A1 | NEW POTENT AND SELECTIVE LIGANDS OF CANNABINOID RECEPTORS | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2006-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090043129-A1 | POTENT AND SELECTIVE LIGANDS OF CANNABINOID RECEPTORS | CNR2, CNR1, GPR18 | CNR2 1/4885CNR1 2/4885TSHR 1694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.