SCHEMBL9698729

SCHEMBL9698729

CN(CCOC[C@]1(CO)CO[C@@H](c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1)Cc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 14/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9697999 1.00 SOAT1 (0.63) SOAT1
SCHEMBL9698739 0.89 SOAT1 (0.74) SOAT1
SCHEMBL9697923 0.89 SOAT1 (0.74) SOAT1
SCHEMBL9699220 0.83 SOAT1 (0.77) SOAT1
SCHEMBL9740337 0.80 SOAT1 (0.77) SOAT1
SCHEMBL9700142 0.80 SOAT1 (0.80) SOAT1
SCHEMBL9698932 0.80 SOAT1 (0.40) SOAT1
SCHEMBL9697969 0.79 SOAT1 (0.79) SOAT1
SCHEMBL9738845 0.78 SOAT1 (0.64) SOAT1
SCHEMBL9738395 0.78 SOAT1 (0.86) SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992017470-A1 IMIDAZOLES RHONE-POULENC RORER LIMITED (GB) 1992-10-15 WO disclosed
EP-0506437-A1 Imidazoles RHONE POULENC RORER LIMITED (GB) 1992-09-30 EP disclosed