Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700239 | 0.89 | SOAT1 (0.47) | SOAT1ACHEALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9700086 | 0.89 | SOAT1 (0.47) | SOAT1ACHEALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9698703 | 0.84 | SOAT1 (0.49) | SOAT1ACHE | |
| SCHEMBL9738313 | 0.83 | SOAT1 (0.39) | SOAT1ALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL9736515 | 0.82 | SOAT1 (0.40) | SOAT1ALDH1A1KDM4E | |
| SCHEMBL9698731 | 0.80 | SOAT1 (0.51) | SOAT1ACHE | |
| SCHEMBL9700125 | 0.80 | SOAT1 (0.50) | SOAT1ACHE | |
| SCHEMBL9697999 | 0.80 | SOAT1 (0.63) | SOAT1 | |
| SCHEMBL9698729 | 0.80 | SOAT1 (0.63) | SOAT1 | |
| SCHEMBL9698755 | 0.79 | SOAT1 (0.43) | SOAT1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017470-A1 | IMIDAZOLES | RHONE-POULENC RORER LIMITED (GB) | 1992-10-15 | — | — | WO | disclosed |
| EP-0506437-A1 | Imidazoles | RHONE POULENC RORER LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |