Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | FAAH | O00519 | 11/20 | 0.44 |
| ▸ | CES1 | P23141 | 6/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50107 | 1.00 | TSHR (0.46) | TSHRFAAHCES1THRBTRPV1 | |
| SCHEMBL2679887 | 1.00 | TSHR (0.46) | TSHRFAAHCES1THRBTRPV1 | |
| SCHEMBL6939659 | 1.00 | TSHR (0.46) | TSHRFAAHCES1THRBTRPV1 | |
| SCHEMBL6932074 | 1.00 | TSHR (0.46) | TSHRFAAHCES1THRBTRPV1 | |
| SCHEMBL5960841 | 1.00 | TSHR (0.46) | TSHRFAAHCES1THRBTRPV1 | |
| SCHEMBL27737023 | 1.00 | TSHR (0.46) | TSHRFAAHCES1THRBTRPV1 | |
| SCHEMBL981371 | 0.97 | TSHR (0.42) | TSHRFAAHCES1THRBTRPV1 | |
| SCHEMBL50560 | 0.89 | — | — | |
| SCHEMBL6934486 | 0.83 | CES1 (0.47) | TSHRFAAHCES1THRBCES2 | |
| SCHEMBL6934662 | 0.83 | CES1 (0.47) | TSHRFAAHCES1THRBCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518636-A1 | Liquid crystal compounds and compositions | SANYO CHEMICAL INDUSTRIES LTD. (JP) | 1992-12-16 | — | — | EP | disclosed |
| EP-0517498-A1 | Liquid crystal compounds and compositions | SANYO CHEMICAL INDUSTRIES LTD. (JP) | 1992-12-09 | — | — | EP | disclosed |
| EP-0500210-A2 | Liquid crystal compounds and compositions | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1992-08-26 | — | — | EP | disclosed |