SCHEMBL50107

SCHEMBL50107

CCCCCC[CH]C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
FAAH O00519 11/20 0.44
CES1 P23141 6/20 0.44
THRB P10828 1/20 0.42
TRPV1 Q8NER1 1/20 0.41
DNM1 Q05193 3/20 0.39
CES2 O00748 1/20 0.38
MEN1 O00255 1/20 0.38
CYP1A2 P05177 1/20 0.38
KMT2A Q03164 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9698734 1.00 TSHR (0.46) TSHRFAAHCES1THRBTRPV1
SCHEMBL2679887 1.00 TSHR (0.46) TSHRFAAHCES1THRBTRPV1
SCHEMBL6939659 1.00 TSHR (0.46) TSHRFAAHCES1THRBTRPV1
SCHEMBL6932074 1.00 TSHR (0.46) TSHRFAAHCES1THRBTRPV1
SCHEMBL5960841 1.00 TSHR (0.46) TSHRFAAHCES1THRBTRPV1
SCHEMBL27737023 1.00 TSHR (0.46) TSHRFAAHCES1THRBTRPV1
SCHEMBL981371 0.97 TSHR (0.42) TSHRFAAHCES1THRBTRPV1
SCHEMBL50560 0.89
SCHEMBL6934486 0.83 CES1 (0.47) TSHRFAAHCES1THRBCES2
SCHEMBL6934662 0.83 CES1 (0.47) TSHRFAAHCES1THRBCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 733 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2202851-A None JP disclosed
JP-4360851-A None JP disclosed
JP-9309864-A None JP disclosed
US-12031079-B2 Polymerisable LC medium and polymer film with flat optical dispersion MERCK PATENT GMBH (DE) 2024-07-09 US disclosed
US-11999717-B2 Triazole carbamate pyridyl sulfonamides as LPA receptor antagonists and uses thereof GILEAD SCIENCES, INC. (US) 2024-06-04 US disclosed
EP-4015598-B1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS MERCK PATENT GMBH (DE) 2024-05-22 EP disclosed
EP-3704176-B1 ORGANIC SEMICONDUCTING COMPOUNDS RAYNERGY TEK INC (TW) 2024-05-15 EP disclosed
US-11958819-B2 Compounds for optically active devices Johnson & Johnson Surgical Vision, Inc. (US) 2024-04-16 US disclosed
EP-3794650-B1 ORGANIC SEMICONDUCTORS RAYNERGY TEK INC (TW) 2024-03-13 EP disclosed
EP-3994234-B1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS MERCK PATENT GMBH (DE) 2024-02-21 EP disclosed
US-5190686-A LIQUID-CRYSTALLINE COPOLYMER IDEMITSU KOSAN CO., LTD. (JP) 1993-03-02 US disclosed
EP-0518636-A1 Liquid crystal compounds and compositions SANYO CHEMICAL INDUSTRIES LTD. (JP) 1992-12-16 EP disclosed
JP-H04360851-A CARBOXYLIC ACID ESTER COMPOUND AND LIQUID CRYSTAL COMPOUND MITSUI PETROCHEM IND LTD 1992-12-14 JP disclosed
EP-0517498-A1 Liquid crystal compounds and compositions SANYO CHEMICAL INDUSTRIES LTD. (JP) 1992-12-09 EP disclosed
EP-0500210-A2 Liquid crystal compounds and compositions SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1992-08-26 EP disclosed
EP-0465344-A1 Liquid crystal compounds Showa Shell Sekiyu Kabushiki Kaisha (JP) 1992-01-08 EP disclosed
EP-0445037-A2 Liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1991-09-04 EP disclosed
EP-0409634-A2 Liquid crystal compounds and optically active compounds SANYO CHEMICAL INDUSTRIES LTD. (JP) 1991-01-23 EP disclosed
JP-H02202851-A OPTICALLY ACTIVE COMPOUND, FERROELECTRIC LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME AND LIQUID CRYSTAL ELEMENT THEREOF SHARP CORP 1990-08-10 JP disclosed
EP-0355772-A2 Liquid-crystalline copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11958819-B2 Compounds for optically active devices PDE6C, ALDH1A2, PDE6A TSHR 3898/4885FAAH 936/4885CES1 2051/4885
US-11999717-B2 Triazole carbamate pyridyl sulfonamides as LPA receptor antagonists and uses thereof LPAR3, LPAR1, LPAR2 TSHR 196/4885FAAH 182/4885CES1 38/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.