Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 4/20 | 0.57 |
| ▸ | THRA | P10827 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.49 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13763431 | 1.00 | NR5A1 (0.61) | NR5A1ESR1THRATHRBLTA4H | |
| SCHEMBL9698564 | 1.00 | NR5A1 (0.61) | NR5A1ESR1THRATHRBLTA4H | |
| SCHEMBL9008243 | 1.00 | NR5A1 (0.61) | NR5A1ESR1THRATHRBLTA4H | |
| SCHEMBL10801503 | 0.95 | ESR1 (0.56) | NR5A1ESR1THRATHRBLTA4H | |
| SCHEMBL25797832 | 0.93 | PDIA6 (0.54) | NR5A1ESR1THRATHRBLTA4H | |
| SCHEMBL25797827 | 0.93 | PDIA6 (0.54) | NR5A1ESR1THRATHRBLTA4H | |
| SCHEMBL3720136 | 0.87 | PTGS1 (0.53) | ESR1LTA4HTP53PDIA6ESR2 | |
| SCHEMBL17445865 | 0.86 | NR5A1 (0.66) | NR5A1THRATHRBLTA4HCNR2 | |
| SCHEMBL13298116 | 0.86 | NR5A1 (0.66) | NR5A1THRATHRBLTA4HCNR2 | |
| SCHEMBL9008240 | 0.86 | NR5A1 (0.66) | NR5A1THRATHRBLTA4HCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147864-A | Bronchodilator agent, antianaphylactic agent, antishock agent, cardiotonic agent and anticarcinogenic agent | AMERICAN CYANAMID COMPANY (US) | 1992-09-15 | — | — | US | disclosed |
| US-4983592-A | Bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID CO. (US) | 1991-01-08 | — | — | US | disclosed |
| EP-0374513-A2 | Novel bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1990-06-27 | — | — | EP | disclosed |
| US-3991139-A | NORBORNENE DERIVATIVES, PHENOLS, ESTER THIOETHERS | SHOWA DENKO KABUSHIKI KAISHA (JA) | 1976-11-09 | — | — | US | disclosed |