Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | CTSE | P14091 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699473 | 0.91 | REN (0.43) | RENCTSDCTSE | |
| SCHEMBL9698109 | 0.90 | REN (0.39) | RENCTSDCTSE | |
| SCHEMBL7291733 | 0.87 | REN (0.42) | REN | |
| SCHEMBL9699394 | 0.86 | REN (0.49) | REN | |
| SCHEMBL7294107 | 0.86 | REN (0.39) | RENCTSE | |
| SCHEMBL7300086 | 0.82 | REN (0.49) | REN | |
| SCHEMBL9700503 | 0.80 | REN (0.50) | REN | |
| SCHEMBL9699238 | 0.79 | REN (0.50) | RENCTSDCTSE | |
| SCHEMBL7301933 | 0.79 | REN (0.51) | REN | |
| SCHEMBL9699254 | 0.77 | REN (0.58) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501280-A2 | Renin-inhibiting peptide analogues | MERCK PATENT GmbH (DE) | 1992-09-02 | — | — | EP | disclosed |