Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.45 |
| ▸ | CNR2 | P34972 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699327 | 0.91 | CNR1 (0.43) | CNR1CNR2CYP3A4MEN1CYP2C9 | |
| SCHEMBL9700377 | 0.88 | CNR1 (0.44) | CNR1CNR2CYP3A4MEN1CYP2C9 | |
| SCHEMBL9700289 | 0.87 | CNR1 (0.54) | CNR1CNR2CYP3A4MEN1CYP2C9 | |
| SCHEMBL9700269 | 0.87 | CNR1 (0.54) | CNR1CNR2CYP3A4MEN1CYP2C9 | |
| SCHEMBL9700352 | 0.86 | CNR1 (0.52) | CNR1CNR2CYP3A4MEN1CYP2C9 | |
| SCHEMBL9701369 | 0.85 | CNR1 (0.51) | CNR1CNR2CYP3A4MEN1CYP2C9 | |
| SCHEMBL9700104 | 0.82 | CNR1 (0.49) | CNR1CNR2CYP3A4MEN1CYP2C9 | |
| SCHEMBL9700097 | 0.81 | CNR1 (0.39) | CNR1CNR2CYP3A4MEN1CYP2C9 | |
| SCHEMBL9728704 | 0.80 | CNR1 (0.42) | CNR1CNR2CYP3A4MEN1CYP2C9 | |
| SCHEMBL9701388 | 0.79 | CNR1 (0.51) | CNR1CNR2CYP3A4MEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112820-A | Vision defects | STERLING DRUG INC. (US) | 1992-05-12 | — | — | US | disclosed |
| US-5109135-A | 2- or 3-aminomethyl-4-amino-3,4-dihydro-2H-1,4-benzoxazine intermediates | STERLING DRUG INC. (US) | 1992-04-28 | — | — | US | disclosed |
| US-5066803-A | Chemical intermediates for analgesics | STERLING DRUG INC. (US) | 1991-11-19 | — | — | US | disclosed |
| US-4939138-A | 2- and 3-aminomethyl-6-arylcarbonyl-2,3-dihydropyrrolo(1,2,3-DE)-1,4-benzoxazines | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |