Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700377 | 0.92 | CNR1 (0.44) | CNR1CNR2MEN1CYP3A4CYP2C9 | |
| SCHEMBL9699327 | 0.89 | CNR1 (0.43) | CNR1CNR2MEN1CYP3A4CYP2C9 | |
| SCHEMBL9700318 | 0.86 | CNR1 (0.51) | CNR1CNR2MEN1CYP3A4CYP2C9 | |
| SCHEMBL9701388 | 0.86 | CNR1 (0.51) | CNR1CNR2MEN1CYP3A4CYP2C9 | |
| SCHEMBL9700267 | 0.85 | CNR1 (0.50) | CNR1CNR2MEN1CYP3A4CYP2C9 | |
| SCHEMBL9701647 | 0.84 | CNR1 (0.49) | CNR1CNR2MEN1CYP3A4CYP2C9 | |
| SCHEMBL9699353 | 0.81 | CNR1 (0.47) | CNR1CNR2MEN1CYP3A4CYP2C9 | |
| SCHEMBL9699345 | 0.80 | CNR1 (0.38) | CNR1CNR2MEN1CYP3A4CYP2C9 | |
| SCHEMBL9699279 | 0.80 | CNR1 (0.45) | CNR1CNR2MEN1CYP3A4CYP2C9 | |
| SCHEMBL9700269 | 0.78 | CNR1 (0.54) | CNR1CNR2MEN1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5109135-A | 2- or 3-aminomethyl-4-amino-3,4-dihydro-2H-1,4-benzoxazine intermediates | STERLING DRUG INC. (US) | 1992-04-28 | — | — | US | disclosed |
| US-5066803-A | Chemical intermediates for analgesics | STERLING DRUG INC. (US) | 1991-11-19 | — | — | US | disclosed |
| WO-1990007505-A1 | 2- AND 3-AMINOMETHYL-6-ARYLCARBONYL-2,3-DIHYDROPYRROLO[1,2,3-de]-1,4-BENZOXAZINES | STERLING DRUG INC. (US) | 1990-07-12 | — | — | WO | disclosed |