Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699371 | 1.00 | NR1I2 (0.45) | NR1I2HTR2CPTGS1ABCB11PDE4D | |
| SCHEMBL9698021 | 0.90 | KMT2A (0.45) | NR1I2HTR2CPTGS1ABCB11PDE4D | |
| SCHEMBL9698026 | 0.90 | KMT2A (0.45) | NR1I2HTR2CPTGS1ABCB11PDE4D | |
| SCHEMBL9697996 | 0.88 | NR1I2 (0.43) | NR1I2HTR2CPTGS1ABCB11PDE4D | |
| SCHEMBL9697987 | 0.88 | NR1I2 (0.43) | NR1I2HTR2CPTGS1ABCB11PDE4D | |
| SCHEMBL9696960 | 0.87 | KMT2A (0.48) | NR1I2HTR2CPTGS1ABCB11PDE4D | |
| SCHEMBL9696953 | 0.87 | KMT2A (0.48) | NR1I2HTR2CPTGS1ABCB11PDE4D | |
| SCHEMBL6362891 | 0.86 | PTGS1 (0.55) | NR1I2HTR2CPTGS1ABCB11PDE4D | |
| SCHEMBL6362892 | 0.86 | PTGS1 (0.55) | NR1I2HTR2CPTGS1ABCB11PDE4D | |
| SCHEMBL10973130 | 0.85 | PTGS1 (0.52) | NR1I2HTR2CPTGS1ABCB11PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158946-A | Antibiotics, bactericides | BEECHAM GROUP P.L.C. (GB) | 1992-10-27 | — | — | US | disclosed |
| EP-0418020-A2 | Cephalosporinderivatives, process for their preparation and pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1991-03-20 | — | — | EP | disclosed |