Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 4/20 | 0.47 |
| ▸ | EIF4H | Q15056 | 4/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701619 | 0.89 | NSD2 (0.47) | NSD2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL16887637 | 0.84 | NSD2 (0.55) | NSD2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11154784 | 0.83 | NSD2 (0.54) | NSD2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL827107 | 0.82 | MEN1 (0.58) | NSD2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL12396143 | 0.81 | NSD2 (0.67) | NSD2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11808999 | 0.80 | P2RX7 (0.62) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL9361672 | 0.79 | NSD2 (0.50) | NSD2MEN1KMT2AALDH1A1LMNA | |
| Acetic Acid SCHEMBL27656229 | 0.79 | NSD2 (0.56) | NSD2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL12396144 | 0.79 | NSD2 (0.53) | NSD2MEN1KMT2AALDH1A1LMNA | |
| Urea SCHEMBL27713673 | 0.78 | NSD2 (0.52) | NSD2MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112820-A | Vision defects | STERLING DRUG INC. (US) | 1992-05-12 | — | — | US | disclosed |
| US-5109135-A | 2- or 3-aminomethyl-4-amino-3,4-dihydro-2H-1,4-benzoxazine intermediates | STERLING DRUG INC. (US) | 1992-04-28 | — | — | US | disclosed |
| US-5066803-A | Chemical intermediates for analgesics | STERLING DRUG INC. (US) | 1991-11-19 | — | — | US | disclosed |
| WO-1990007505-A1 | 2- AND 3-AMINOMETHYL-6-ARYLCARBONYL-2,3-DIHYDROPYRROLO[1,2,3-de]-1,4-BENZOXAZINES | STERLING DRUG INC. (US) | 1990-07-12 | — | — | WO | disclosed |
| US-4939138-A | 2- and 3-aminomethyl-6-arylcarbonyl-2,3-dihydropyrrolo(1,2,3-DE)-1,4-benzoxazines | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |