Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.31 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507616 | 0.72 | NOTUM (0.37) | NOTUM | |
| SCHEMBL9508175 | 0.68 | AHR (0.58) | AHRMAPK1FLT1BCHEACHE | |
| SCHEMBL9511385 | 0.68 | AHR (0.60) | AHRFLT1 | |
| SCHEMBL22180420 | 0.67 | AHR (0.47) | AHRBCHEACHENOX1 | |
| SCHEMBL11066611 | 0.67 | AHR (0.43) | AHRBCHEACHENOX1 | |
| SCHEMBL987352 | 0.66 | IDO1 (0.50) | CYP3A4TSHRMAPK1TDP1TMPRSS4 | |
| SCHEMBL29403188 | 0.66 | TSHR (0.62) | CYP3A4TSHRMAPK1TDP1TMPRSS4 | |
| SCHEMBL29649700 | 0.66 | IDO1 (0.50) | CYP3A4TSHRMAPK1TDP1TMPRSS4 | |
| SCHEMBL107751 | 0.66 | TSHR (0.62) | CYP3A4TSHRMAPK1TDP1TMPRSS4 | |
| SCHEMBL9510151 | 0.65 | AHR (0.44) | AHRTDP1FLT1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5095157-A | Friedel-crafts catalyst | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |