Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.55 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 6/20 | 0.49 |
| ▸ | CNR1 | P21554 | 5/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11331625 | 0.86 | HTR2A (0.51) | ALOX5TSHRMEN1MAPTHTT | |
| SCHEMBL11237619 | 0.86 | HTR2A (0.51) | ALOX5TSHRMEN1MAPTHTT | |
| SCHEMBL15532718 | 0.82 | ALOX5 (0.66) | ALOX5TSHRMEN1TP53CYP3A4 | |
| SCHEMBL20357443 | 0.82 | ALOX5 (0.66) | ALOX5TSHRMEN1TP53CYP3A4 | |
| SCHEMBL8053988 | 0.81 | ALOX5 (0.49) | ALOX5TSHRMEN1TP53CYP3A4 | |
| SCHEMBL11871738 | 0.80 | SMPD1 (0.55) | LTB4RLTB4R2ALOX5MEN1CYP3A4 | |
| SCHEMBL15868713 | 0.80 | ALOX5 (0.63) | ALOX5TSHRMEN1TP53CYP3A4 | |
| SCHEMBL15868714 | 0.80 | ALOX5 (0.63) | ALOX5TSHRMEN1TP53CYP3A4 | |
| SCHEMBL4879945 | 0.80 | ALOX5 (0.68) | ALOX5TSHRMEN1TP53CYP3A4 | |
| SCHEMBL2348704 | 0.80 | ALOX5 (0.68) | ALOX5TSHRMEN1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147864-A | Bronchodilator agent, antianaphylactic agent, antishock agent, cardiotonic agent and anticarcinogenic agent | AMERICAN CYANAMID COMPANY (US) | 1992-09-15 | — | — | US | disclosed |
| US-4983592-A | Bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID CO. (US) | 1991-01-08 | — | — | US | disclosed |
| EP-0374513-A2 | Novel bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1990-06-27 | — | — | EP | disclosed |