SCHEMBL9699736

SCHEMBL9699736

CCC(c1ccc(OC(C)=O)cc1)c1ccc(OC(C)=O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.53
ELANE P08246 2/20 0.52
ESR1 P03372 2/20 0.51
HIF1A Q16665 2/20 0.51
HSD17B10 Q99714 1/20 0.50
CYP19A1 P11511 1/20 0.49
MAPT P10636 3/20 0.49
GAA P10253 3/20 0.49
ALDH1A1 P00352 2/20 0.49
HSP90AA1 P07900 1/20 0.49
POLB P06746 1/20 0.48
PKM P14618 1/20 0.48
KDM4E B2RXH2 3/20 0.47
TSHR P16473 2/20 0.47
CYP3A4 P08684 2/20 0.47
ABCB11 O95342 1/20 0.47
ADRA2A P08913 1/20 0.47
CYP2C9 P11712 1/20 0.47
PDE4A P27815 1/20 0.47
ADRA1A P35348 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12445339 0.93 CYP17A1 (0.54) LMNAELANEESR1HIF1AHSD17B10
SCHEMBL12521562 0.93 LMNA (0.47) LMNAELANEESR1HIF1AHSD17B10
SCHEMBL13986172 0.85 CYP17A1 (0.47) LMNAELANEESR1HIF1AHSD17B10
SCHEMBL2246272 0.85 ESR1 (0.71) LMNAELANEESR1HIF1AHSD17B10
SCHEMBL31356495 0.85 ESR1 (0.71) LMNAELANEESR1HIF1AHSD17B10
SCHEMBL13986174 0.84 ELANE (0.53) LMNAELANEHSD17B10MAPTFAAH
Acetic Acid SCHEMBL4242571 0.84 LMNA (0.50) LMNAELANEESR1HIF1AHSD17B10
SCHEMBL10591542 0.84 ESR1 (0.47) LMNAELANEESR1HIF1AHSD17B10
SCHEMBL21612683 0.83 ESR1 (0.69) LMNAELANEESR1HIF1AHSD17B10
SCHEMBL111718 0.83 TSHR (0.60) LMNAELANEESR1HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113831522-A Preparation method of low-dielectric high-viscosity LCP material 宁夏清研高分子新材料有限公司 2021-12-24 CN disclosed
US-5086158-A Liquid crystalline polymer with good heat resistance and melt processability POLYPLASTICS CO., LTD. (JP) 1992-02-04 US disclosed
US-5049643-A Molding materials; radiation transparent; heat resistance;fillers POLYPLASTICS CO., LTD. (JP) 1991-09-17 US disclosed
EP-0426481-A2 Polyester resin exhibiting anisotropy in a molten state and resin composition POLYPLASTICS CO. LTD. (JP) 1991-05-08 EP disclosed
EP-0388124-A2 Wholly aromatic polyester and composition containing the same POLYPLASTICS CO. LTD. (JP) 1990-09-19 EP disclosed