Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.58 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 10/20 | 0.46 |
| ▸ | CA1 | P00915 | 10/20 | 0.46 |
| ▸ | CA2 | P00918 | 10/20 | 0.46 |
| ▸ | CA9 | Q16790 | 10/20 | 0.46 |
| ▸ | COMT | P21964 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6348803 | 0.81 | TYR (0.55) | TYRDOHHKDM4ECA12CA1 | |
| SCHEMBL11636925 | 0.79 | AKR1B1 (0.50) | TYRDOHHKDM4EAKR1B1CA12 | |
| SCHEMBL11504712 | 0.79 | AKR1B1 (0.50) | TYRDOHHKDM4EAKR1B1CA12 | |
| SCHEMBL11503583 | 0.79 | AKR1B1 (0.50) | TYRDOHHKDM4EAKR1B1CA12 | |
| SCHEMBL11504689 | 0.79 | AKR1B1 (0.50) | TYRDOHHKDM4EAKR1B1CA12 | |
| SCHEMBL11504046 | 0.79 | AKR1B1 (0.50) | TYRDOHHKDM4EAKR1B1CA12 | |
| SCHEMBL5517575 | 0.79 | KDM4E (0.53) | TYRDOHHKDM4ECA12CA1 | |
| SCHEMBL9705983 | 0.78 | AKR1B1 (0.49) | TYRDOHHKDM4EAKR1B1CA12 | |
| SCHEMBL9704932 | 0.78 | TYR (0.51) | TYRDOHHKDM4ECA12CA1 | |
| SCHEMBL7640934 | 0.76 | TYR (0.53) | TYRDOHHKDM4ECA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992012131-A1 | 3-HYDROXYPYRIDIN-4-ONE DERIVATIVES AS PHARMACEUTICAL COMPOSITIONS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1992-07-23 | — | — | WO | claimed |
| EP-0494754-A1 | 3-hydroxypyridin-4-one derivatives as pharmaceutical compositions | BRITISH TECHNOLOGY GROUP LTD (GB) | 1992-07-15 | — | — | EP | claimed |
| US-4153693-A | 1,4-Dihydro-4-oxo-pyridylacetamido cephalosporins and their utilization as medicinal agents for combating bacterial infections | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-05-08 | — | — | US | disclosed |
| US-4119775-A | ANTIBACTERIAL | RICHARDSON-MERRELL INC. (US) | 1978-10-10 | — | — | US | disclosed |
| US-3989687-A | ANTIBACTERIAL | RICHARDSON-MERRELL INC. (US) | 1976-11-02 | — | — | US | disclosed |