Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | F13A1 | P00488 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5517575 | 0.95 | KDM4E (0.53) | TYRDOHHKDM4ETBXAS1FABP4 | |
| SCHEMBL6348803 | 0.88 | TYR (0.55) | TYRDOHHKDM4EFABP4FABP5 | |
| SCHEMBL30983057 | 0.79 | NPC1 (0.49) | TYRDOHHKDM4EPTGS1PTGS2 | |
| SCHEMBL30982965 | 0.79 | NPC1 (0.49) | TYRDOHHKDM4EPTGS1PTGS2 | |
| SCHEMBL30982680 | 0.79 | NPC1 (0.49) | TYRDOHHKDM4EPTGS1PTGS2 | |
| SCHEMBL9453872 | 0.78 | TYR (0.50) | TYRDOHHKDM4EMAOBCOMT | |
| SCHEMBL9700040 | 0.78 | TYR (0.58) | TYRDOHHKDM4EMAOBCOMT | |
| SCHEMBL17267401 | 0.77 | TBXAS1 (0.46) | KDM4ETBXAS1FABP4FABP5PTGS1 | |
| SCHEMBL17128963 | 0.74 | DOHH (0.50) | TYRDOHHKDM4EMAOBCOMT | |
| SCHEMBL7640934 | 0.70 | TYR (0.53) | TYRDOHHKDM4EMAOBCOMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992012131-A1 | 3-HYDROXYPYRIDIN-4-ONE DERIVATIVES AS PHARMACEUTICAL COMPOSITIONS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1992-07-23 | — | — | WO | disclosed |