Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 15/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PDE6D | O43924 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700146 | 1.00 | SOAT1 (0.43) | SOAT1CFTRALDH1A1PDE6DALDH2 | |
| SCHEMBL9697807 | 0.89 | SOAT1 (0.43) | SOAT1CFTRALDH1A1PDE6DALDH2 | |
| SCHEMBL9700192 | 0.89 | SOAT1 (0.43) | SOAT1CFTRALDH1A1PDE6DALDH2 | |
| SCHEMBL9700095 | 0.89 | SOAT1 (0.43) | SOAT1CFTRALDH1A1PDE6DALDH2 | |
| SCHEMBL9697997 | 0.89 | SOAT1 (0.43) | SOAT1CFTRALDH1A1PDE6DALDH2 | |
| SCHEMBL9698755 | 0.89 | SOAT1 (0.43) | SOAT1CFTRALDH1A1PDE6DALDH2 | |
| SCHEMBL9737457 | 0.89 | SOAT1 (0.48) | SOAT1CFTRALDH1A1PDE6DALDH2 | |
| SCHEMBL9852391 | 0.87 | SOAT1 (0.42) | SOAT1CFTRALDH1A1HPGD | |
| SCHEMBL9700090 | 0.85 | SOAT1 (0.51) | SOAT1CFTR | |
| SCHEMBL9737635 | 0.83 | SOAT1 (0.38) | SOAT1CFTRALDH1A1PDE6DALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017470-A1 | IMIDAZOLES | RHONE-POULENC RORER LIMITED (GB) | 1992-10-15 | — | — | WO | disclosed |
| EP-0506437-A1 | Imidazoles | RHONE POULENC RORER LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |