Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PDE6D | O43924 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737457 | 0.88 | SOAT1 (0.48) | SOAT1ALDH1A1KDM4ECFTRHPGD | |
| SCHEMBL9700192 | 0.86 | SOAT1 (0.43) | SOAT1ALDH1A1KDM4ECFTRPDE6D | |
| SCHEMBL9698755 | 0.86 | SOAT1 (0.43) | SOAT1ALDH1A1KDM4ECFTRPDE6D | |
| SCHEMBL9700121 | 0.83 | SOAT1 (0.43) | SOAT1ALDH1A1KDM4ECFTRHPGD | |
| SCHEMBL9700146 | 0.83 | SOAT1 (0.43) | SOAT1ALDH1A1KDM4ECFTRHPGD | |
| SCHEMBL9700095 | 0.83 | SOAT1 (0.43) | SOAT1ALDH1A1KDM4ECFTRHPGD | |
| SCHEMBL9697997 | 0.83 | SOAT1 (0.43) | SOAT1ALDH1A1KDM4ECFTRHPGD | |
| SCHEMBL9697807 | 0.83 | SOAT1 (0.43) | SOAT1ALDH1A1KDM4ECFTRHPGD | |
| SCHEMBL9738313 | 0.83 | SOAT1 (0.39) | SOAT1ALDH1A1KDM4ECFTRHPGD | |
| SCHEMBL9699343 | 0.83 | CFTR (0.39) | SOAT1ALDH1A1KDM4ECFTRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102900-A | Antilipemic and anticholesterol agents | RHONE-POULENC RORER S.A. (FR) | 1992-04-07 | — | — | US | disclosed |