Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 9/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4616226 | 0.87 | FBP1 (0.46) | FBP1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL4615169 | 0.85 | FBP1 (0.46) | FBP1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL9701316 | 0.85 | FBP1 (0.45) | FBP1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL4614758 | 0.81 | FBP1 (0.45) | FBP1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL4692295 | 0.80 | PPARA (0.66) | FBP1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL1549824 | 0.80 | FBP1 (0.58) | FBP1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL4614921 | 0.80 | FBP1 (0.44) | FBP1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL4616212 | 0.80 | FBP1 (0.44) | FBP1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL14543831 | 0.80 | EPAS1 (0.50) | FBP1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL4615988 | 0.79 | FBP1 (0.47) | FBP1PPARAABCB11CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116987-A | METHOD OF PREPARING CHROMAN DERIVATIVES, AND SYNTHESIS INTERMEDIATES | SANOFI (FR) | 1992-05-26 | — | — | US | disclosed |
| US-5071991-A | METHOD OF PREPARING CHROMAN DERIVATIVES, AND SYNTHESIS INTERMEDIATES | SANOFI (FR) | 1991-12-10 | — | — | US | disclosed |