Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.63 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.63 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727849 | 0.94 | PPARG (0.62) | AGTR1AGTR2PPARG | |
| SCHEMBL9700315 | 0.91 | AGTR1 (0.58) | AGTR1AGTR2PPARG | |
| SCHEMBL9701114 | 0.87 | AGTR1 (0.66) | AGTR1AGTR2PPARG | |
| SCHEMBL9701107 | 0.86 | AGTR1 (0.65) | AGTR1AGTR2PPARG | |
| SCHEMBL9702813 | 0.83 | AGTR1 (0.60) | AGTR1AGTR2PPARG | |
| SCHEMBL7851749 | 0.81 | AGTR1 (0.67) | AGTR1AGTR2PPARG | |
| SCHEMBL9700411 | 0.81 | PPARG (0.64) | AGTR1AGTR2PPARG | |
| SCHEMBL9702760 | 0.81 | PPARG (0.64) | AGTR1AGTR2PPARG | |
| SCHEMBL9702328 | 0.80 | PPARG (0.63) | AGTR1AGTR2PPARG | |
| SCHEMBL9702667 | 0.80 | AGTR1 (0.68) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497516-A1 | Substituted pyrrolo-fused 6-membered heterocycles as angiotensin II antagonists | MERCK & CO. INC. (US) | 1992-08-05 | — | — | EP | disclosed |
| US-5124335-A | Hypotensive agents, antiglaucoma agents | MERCK & CO., INC. (US) | 1992-06-23 | — | — | US | disclosed |